IL8 monoclonal antibody (M05), clone 6G4
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant IL8.
Immunogen
IL8 (AAH13615.1, 21 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
EGAVLPRSAKELRCQCIKTYSKPFHPKFIKELRVIESGPHCANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.32 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of IL8 expression in transfected 293T cell line by IL8 monoclonal antibody (M05), clone 6G4.
Lane 1: IL8 transfected lysate(11.1 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged IL8 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — IL8
Entrez GeneID
3576GeneBank Accession#
BC013615.1Protein Accession#
AAH13615.1Gene Name
IL8
Gene Alias
CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1
Gene Description
interleukin 8
Omim ID
146930Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq
Other Designations
T cell chemotactic factor|beta-thromboglobulin-like protein|chemokine (C-X-C motif) ligand 8|emoctakin|granulocyte chemotactic protein 1|lymphocyte-derived neutrophil-activating factor|monocyte-derived neutrophil chemotactic factor|neutrophil-activating p
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Interactome
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Pathway
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Disease
- Acute Disease
- Adenocarcinoma
- Adenomatous Polyps
- Alcoholism
- Alzheimer disease
- Appetite
- Arthritis
- Asthma
- Atherosclerosis
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