IL6 monoclonal antibody (M03), clone 3F4
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More Files
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Specifications
Product Description
Mouse monoclonal antibody raised against a full-length recombinant IL6.
Immunogen
IL6 (NP_000591, 29 a.a.-212 a.a.) full-length recombinant protein.
Sequence
SPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (21 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of IL6 expression in transfected 293T cell line by IL6 monoclonal antibody (M03), clone 3F4.
Lane 1: IL6 transfected lysate(23.7 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to IL6 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — IL6
Entrez GeneID
3569GeneBank Accession#
NM_000600Protein Accession#
NP_000591Gene Name
IL6
Gene Alias
BSF2, HGF, HSF, IFNB2, IL-6
Gene Description
interleukin 6 (interferon, beta 2)
Gene Ontology
HyperlinkGene Summary
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq
Other Designations
interleukin 6
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Interactomes
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Pathways
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Diseases
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