IL6 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human IL6 protein.
Immunogen
IL6 (AAH15511, 1 a.a. ~ 212 a.a) full-length human protein.
Sequence
MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of IL6 expression in transfected 293T cell line (H00003569-T01) by IL6 MaxPab polyclonal antibody.
Lane 1: IL6 transfected lysate(23.32 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to IL6 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — IL6
Entrez GeneID
3569GeneBank Accession#
BC015511Protein Accession#
AAH15511Gene Name
IL6
Gene Alias
BSF2, HGF, HSF, IFNB2, IL-6
Gene Description
interleukin 6 (interferon, beta 2)
Gene Ontology
HyperlinkGene Summary
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq
Other Designations
interleukin 6
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Interactome
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Pathway
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Disease
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Publication Reference
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Cancer-associated fibroblasts affect breast cancer cell gene expression, invasion and angiogenesis.
Eiro N, Gonzalez L, Martinez-Ordonez A, Fernandez-Garcia B, Gonzalez LO, Cid S, Dominguez F, Perez-Fernandez R, Vizoso FJ.
Cellular Oncology (Dordrecht) 2018 Mar; [Epub].
Application:IHC, Human, MDA-MB-231 cells.
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Cancer-associated fibroblasts affect breast cancer cell gene expression, invasion and angiogenesis.
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