CYR61 monoclonal antibody (M06), clone 3C11
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant CYR61.
Immunogen
CYR61 (AAH16952.1, 25 a.a. ~ 381 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
TCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYRLFNDIHKFRD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CYR61 is 1 ng/ml as a capture antibody.ELISA
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Gene Info — CYR61
Entrez GeneID
3491GeneBank Accession#
BC016952Protein Accession#
AAH16952.1Gene Name
CYR61
Gene Alias
CCN1, GIG1, IGFBP10
Gene Description
cysteine-rich, angiogenic inducer, 61
Omim ID
602369Gene Ontology
HyperlinkGene Summary
CYR61 is a secreted, cysteine-rich, heparin-binding protein encoded by a growth factor-inducible immediate-early gene. Acting as an extracellular, matrix-associated signaling molecule, CYR61 promotes the adhesion of endothelial cells through interaction with integrin and augments growth factor-induced DNA synthesis in the same cell type.[supplied by OMIM
Other Designations
OTTHUMP00000012303|cysteine-rich heparin-binding protein 61|cysteine-rich, anigogenic inducer, 61
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Interactome
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Disease
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