IFNAR2 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human IFNAR2 protein.
Immunogen
IFNAR2 (AAH02793.1, 1 a.a. ~ 331 a.a) full-length human protein.
Sequence
MLLSQNAFIVRSLNLVLMVYISLVFGISYDSPDYTDESCTFKISLRNFRSILSWELKNHSIVPTHYTLLYTIMSKPEDLKVVKNCANTTRSFCDLTDEWRSTHEAYVTVLEGFSGNTTLFSCSHNFWLAIDMSFEPPEFEIVGFTNHINVMVKFPSIVEEELQFDLSLVIEEQSEGIVKKHKPEIKGNMSGNFTYIIDKLIPNTNYCVSVYLEHSDEQAVIKSPLKCTLLPPGQESESAESAKIGGIITVFLIALVLTSTIVTLKWIGYICLRNSLPKVLRQGLTKGWNAVAIHRCSHNALQSETPELKQSSCLSFPSSWDYKRASLCPSD
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of IFNAR2 expression in transfected 293T cell line (H00003455-T02) by IFNAR2 MaxPab polyclonal antibody.
Lane 1: IFNAR2 transfected lysate(37.40 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — IFNAR2
Entrez GeneID
3455GeneBank Accession#
BC002793Protein Accession#
AAH02793.1Gene Name
IFNAR2
Gene Alias
IFN-R, IFN-alpha-REC, IFNABR, IFNARB
Gene Description
interferon (alpha, beta and omega) receptor 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000067674|OTTHUMP00000067676|human interferon alpha/beta receptor|interferon alpha/beta receptor 2|interferon-alpha/beta receptor beta chain|type I interferon receptor
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Interactome
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Pathway
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Disease
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