HTR7 (Human) Recombinant Protein (P01)
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Specification
Product Description
Human HTR7 full-length ORF ( NP_062874.1, 1 a.a. - 432 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
74.4
Interspecies Antigen Sequence
Mouse (95); Rat (96)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — HTR7
Entrez GeneID
3363GeneBank Accession#
NM_019860.2Protein Accession#
NP_062874.1Gene Name
HTR7
Gene Alias
5-HT7
Gene Description
5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
Omim ID
182137Gene Ontology
HyperlinkGene Summary
The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq
Other Designations
5-hydroxytryptamine receptor 7|OTTHUMP00000020077|OTTHUMP00000020078|OTTHUMP00000020079|serotonin 5-HT-7 receptor
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Interactome
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Pathway
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Disease
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