HPGD MaxPab mouse polyclonal antibody (B01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human HPGD protein.
Immunogen
HPGD (AAH18986.1, 1 a.a. ~ 266 a.a) full-length human protein.
Sequence
MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNGAIMKITTSKGIHFQDYDTTPFQAKTQ
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Tissue lysate)
HPGD MaxPab polyclonal antibody. Western Blot analysis of HPGD expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of HPGD expression in transfected 293T cell line (H00003248-T01) by HPGD MaxPab polyclonal antibody.
Lane 1: HPGD transfected lysate(29.37 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — HPGD
Entrez GeneID
3248GeneBank Accession#
BC018986Protein Accession#
AAH18986Gene Name
HPGD
Gene Alias
15-PGDH, PGDH, PGDH1, SDR36C1
Gene Description
hydroxyprostaglandin dehydrogenase 15-(NAD)
Omim ID
601688Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
15-hydroxy prostaglandin dehydrogenase|15-hydroxyprostaglandin dehydrogenase|NAD+-dependent 15-hydroxyprostaglandin dehydrogenase|short chain dehydrogenase/reductase family 36C, member 1
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Interactome
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Disease
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Publication Reference
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NAD+-Dependent 15-Hydroxyprostaglandin Dehydrogenase Regulates Levels of Bioactive Lipids in Non-Small Cell Lung Cancer.
Hughes D, Otani T, Yang P, Newman RA, Yantiss RK, Altorki NK, Port JL, Yan M, Markowitz SD, Mazumdar M, Tai HH, Subbaramaiah K, Dannenberg AJ.
Cancer Prevention Research (Philadelphia, Pa.) 2008 Sep; 1(4):241.
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NAD+-Dependent 15-Hydroxyprostaglandin Dehydrogenase Regulates Levels of Bioactive Lipids in Non-Small Cell Lung Cancer.
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