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Last updated: 2014/4/14
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BIOtech
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HLA-DRA MaxPab rabbit polyclonal antibody (D01)MaxPab

  • Catalog # : H00003122-D01
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against a full-length human HLA-DRA protein.
  • Immunogen:
  • HLA-DRA (NP_061984.2, 1 a.a. ~ 254 a.a) full-length human protein.
  • Sequence:
  • MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFIIKGLRKSNAAERRGPL
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • HLA-DRA MaxPab rabbit polyclonal antibody. Western Blot analysis of HLA-DRA expression in A-431.
  • Protocol Download
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of HLA-DRA expression in transfected 293T cell line (H00003122-T03) by HLA-DRA MaxPab polyclonal antibody.

    Lane 1: HLA-DRA transfected lysate(28.60 KDa).
    Lane 2: Non-transfected lysate.
  • Protocol Download
  • Immunoprecipitation
  • Immunoprecipitation
  • Immunoprecipitation of HLA-DRA transfected lysate using anti-HLA-DRA MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with HLA-DRA MaxPab mouse polyclonal antibody (B02) (H00003122-B02).
  • Protocol Download
  • Detection Antibody
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Detection Antibody
  • Gene Information
  • Entrez GeneID:
  • 3122
  • Gene Name:
  • HLA-DRA
  • Gene Alias:
  • HLA-DRA1
  • Gene Description:
  • major histocompatibility complex, class II, DR alpha
  • Gene Summary:
  • HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq
  • Other Designations:
  • HLA class II histocompatibility antigen, DR alpha chain,MHC cell surface glycoprotein,histocompatibility antigen HLA-DR alpha
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