HINT1 polyclonal antibody (A01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant HINT1.
Immunogen
HINT1 (NP_005331, 59 a.a. ~ 126 a.a) partial recombinant protein with GST tag.
Sequence
HISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (33.59 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — HINT1
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Interactome
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Disease
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Publication Reference
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HINT1 protein: A new therapeutic target to enhance opioid antinociception and block mechanical allodynia.
Garzon J, Herrero-Labrador R, Rodriguez-Munoz M, Shah R, Vicente-Sanchez A, Wagner CR, Sanchez-Blazquez P.
Neuropharmacology 2015 Feb; 89:412.
Application:WB, Mouse, Mesencephalic Periaqueductal Grey Matter.
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HINT1 protein cooperates with cannabinoid 1 receptor to negatively regulate glutamate NMDA receptor activity.
Vicente-Sanchez A, Sanchez-Blazquez P, Rodriguez-Munoz M, Garzon J.
Molecular Brain 2013 Oct; 6(1):42.
Application:WB-Ce, WB-Tr, Mouse, Cortical cell.
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The histidine triad nucleotide-binding protein 1 supports mu-opioid receptor-glutamate NMDA receptor cross-regulation.
Rodriguez-Munoz M, Ssnchez-Blazquez P, Vicente-Sanchez A, Bailon C, Martin-Aznar B, Garzon J.
Cell Mol Life Sci 2010 Dec; 68:2933.
Application:WB-Ti, Mouse, Cerebral cortex.
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HINT1 protein: A new therapeutic target to enhance opioid antinociception and block mechanical allodynia.
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