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Last updated: 2014/8/18
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HFE purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00003077-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human HFE protein.
  • Immunogen:
  • HFE (NP_000401.1, 1 a.a. ~ 348 a.a) full-length human protein.
  • Sequence:
  • MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Flow Cytometry
  • Flow Cytometry enlargeenlarge this image
  • FACS analysis of negative control 293 cells (Black) and HFE expressing 293 cells (Green) using HFE purified MaxPab mouse polyclonal antibody.
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • HFE MaxPab polyclonal antibody. Western Blot analysis of HFE expression in HepG2.
  • Protocol Download
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of HFE expression in transfected 293T cell line (H00003077-T01) by HFE MaxPab polyclonal antibody.

    Lane 1: HFE transfected lysate(38.28 KDa).
    Lane 2: Non-transfected lysate.
  • Protocol Download
  • Detection Antibody
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Detection Antibody
  • Gene Information
  • Entrez GeneID:
  • 3077
  • Gene Name:
  • HFE
  • Gene Alias:
  • HFE1,HH,HLA-H,MGC103790,dJ221C16.10.1
  • Gene Description:
  • hemochromatosis
  • Gene Summary:
  • The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq
  • Other Designations:
  • MHC class I-like protein HFE,hemochromatosis protein,hereditary hemochromatosis protein HLA-H
  • Related Disease
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