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Last updated: 2014/7/21
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HFE polyclonal antibody (A01)

  • Catalog # : H00003077-A01
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a partial recombinant HFE.
  • Immunogen:
  • HFE (NP_000401, 115 a.a. ~ 205 a.a) partial recombinant protein with GST tag.
  • Sequence:
  • SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQ
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.
  • Storage Buffer:
  • 50 % glycerol
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3077
  • Gene Name:
  • HFE
  • Gene Alias:
  • HFE1,HH,HLA-H,MGC103790,dJ221C16.10.1
  • Gene Description:
  • hemochromatosis
  • Gene Summary:
  • The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq
  • Other Designations:
  • MHC class I-like protein HFE,hemochromatosis protein,hereditary hemochromatosis protein HLA-H
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