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CFH (Human) Recombinant Protein (P02)

  • Catalog # : H00003075-P02
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Human CFH full-length ORF ( AAH20687, 1 a.a. - 195 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • MLLLINVVLTLWVSCANGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSYMVFCISY
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 47.19
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00003075-P02
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Entrez GeneID:
  • 3075
  • Gene Name:
  • CFH
  • Gene Alias:
  • ARMD4,ARMS1,CFHL3,FH,FHL1,HF,HF1,HF2,HUS,MGC88246
  • Gene Description:
  • complement factor H
  • Gene Summary:
  • This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
  • Other Designations:
  • H factor 1 (complement),H factor 2 (complement),OTTHUMP00000033598,age-related maculopathy susceptibility 1,beta-1-H-globulin,beta-1H,complement factor H, isoform b,factor H,factor H-like 1
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