HSD17B10 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
HSD17B10 transfected lysate.
Western Blot
Lane 1: HSD17B10 transfected lysate ( 28.82 KDa)
Lane 2: Non-transfected lysate.
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Specification
Product Description
Transfected Cell Line
293T
Plasmid
pCMV-HADH2 full-length
Host
Human
Theoretical MW (kDa)
28.82
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-HADH2 antibody (H00003028-B01) by Western Blots.
SDS-PAGE Gel
HSD17B10 transfected lysate.
Western Blot
Lane 1: HSD17B10 transfected lysate ( 28.82 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — HSD17B10
Entrez GeneID
3028GeneBank Accession#
NM_004493.2Protein Accession#
NP_004484.1Gene Name
HSD17B10
Gene Alias
17b-HSD10, ABAD, CAMR, DUPXp11.22, ERAB, HADH2, HCD2, MHBD, MRPP2, MRX17, MRX31, MRXS10, SCHAD, SDR5C1
Gene Description
hydroxysteroid (17-beta) dehydrogenase 10
Gene Ontology
HyperlinkGene Summary
This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq
Other Designations
17-beta-hydroxysteroid dehydrogenase type 10|3-hydroxy-2-methylbutyryl-CoA dehydrogenase|AB-binding alcohol dehydrogenase|OTTHUMP00000023348|OTTHUMP00000023349|amyloid-beta binding polypeptide|amyloid-beta peptide binding alcohol dehydrogenase|mental reta
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Interactome
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Pathway
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