CXCL1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CXCL1 full-length
Host
Human
Theoretical MW (kDa)
11.3
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CXCL1 antibody (H00002919-D01P) by Western Blots.
SDS-PAGE Gel
CXCL1 transfected lysate.
Western Blot
Lane 1: CXCL1 transfected lysate ( 11.30 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CXCL1
Entrez GeneID
2919GeneBank Accession#
NM_001511Protein Accession#
NP_001502.1Gene Name
CXCL1
Gene Alias
FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1
Gene Description
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
Omim ID
155730Gene Ontology
HyperlinkGene Summary
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CXC chemokines are further subdivided into ELR and non-ELR types based on the presence or absence of a glu-leu-arg sequence adjacent and N terminal to the CXC motif. ELR types are chemotactic for neutrophils, while non-ELR types are chemotactic for lymphocytes.[supplied by OMIM
Other Designations
GRO1 oncogene (melanoma growth stimulating activity, alpha)|GRO1 oncogene (melanoma growth-stimulating activity)|MGSA alpha|chemokine (C-X-C motif) ligand 1|fibroblast secretory protein|melanoma growth stimulatory activity alpha
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Interactome
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