GM2A monoclonal antibody (M02), clone 2C8
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GM2A is 0.3 ng/ml as a capture antibody.
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant GM2A.
Immunogen
GM2A (NP_000396.2, 94 a.a. ~ 193 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
WIKIPCTDYIGSCTFEHFCDVLDMLIPTGEPCPEPLRTYGLPCHCPFKEGTYSLPKSEFVVPDLELPSWLTTGNYRIESVLSSSGKRLGCIKIAASLKGI
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GM2A is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — GM2A
Entrez GeneID
2760GeneBank Accession#
NM_000405Protein Accession#
NP_000396.2Gene Name
GM2A
Gene Alias
SAP-3
Gene Description
GM2 ganglioside activator
Omim ID
272750Gene Ontology
HyperlinkGene Summary
This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. [provided by RefSeq
Other Designations
cerebroside sulfate activator protein|sphingolipid activator protein 3
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Interactome
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Pathway
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Disease
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