GCLM purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human GCLM protein.
Immunogen
GCLM (NP_002052.1, 1 a.a. ~ 274 a.a) full-length human protein.
Sequence
MGTDSRAAKALLARARTLHLQTGNLLNWGRLRKKCPSTHSEELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIQAHEWVPLWLLRYSVIVKSRGIIKSKGYILQAKRRGS
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
GCLM MaxPab polyclonal antibody. Western Blot analysis of GCLM expression in human liver.Western Blot (Cell lysate)
GCLM MaxPab polyclonal antibody. Western Blot analysis of GCLM expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of GCLM expression in transfected 293T cell line (H00002730-T01) by GCLM MaxPab polyclonal antibody.
Lane 1: GCLM transfected lysate(30.14 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — GCLM
Entrez GeneID
2730GeneBank Accession#
NM_002061.2Protein Accession#
NP_002052.1Gene Name
GCLM
Gene Alias
GLCLR
Gene Description
glutamate-cysteine ligase, modifier subunit
Omim ID
601176Gene Ontology
HyperlinkGene Summary
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq
Other Designations
GSC light chain|OTTHUMP00000012299|gamma-glutamylcysteine synthetase|glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD)|glutamate-cysteine ligase regulatory protein
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Interactome
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Pathway
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Disease
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