Immunoprecipitation of GFAP transfected lysate using anti-GFAP MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with GFAP purified MaxPab mouse polyclonal antibody (B01P) (H00002670-B01P).
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq