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Last updated: 2014/10/27

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GBA Pre-design Chimera RNAi

  • Catalog # : H00002629-R05
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  • Specification
  • Product Description:
  • Homo sapiens glucosidase, beta; acid (includes glucosylceramidase) (GBA), transcript variant 5, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_001005750
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 2629
  • Gene Name:
  • GBA
  • Gene Alias:
  • GBA1,GCB,GLUC
  • Gene Description:
  • glucosidase, beta; acid (includes glucosylceramidase)
  • Gene Summary:
  • This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
  • Other Designations:
  • D-glucosyl-N-acylsphingosine glucohydrolase,OTTHUMP00000033992,OTTHUMP00000033993,glucocerebrosidase,glucocerebrosidase (alt.),lysosomal glucocerebrosidase
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