GAPDH purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
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Specifications
Product Description
Rabbit polyclonal antibody raised against a full-length human GAPDH protein.
Immunogen
GAPDH (NP_002037.2, 1 a.a. ~ 335 a.a) full-length human protein.
Sequence
MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE
Host
Rabbit
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
GAPDH MaxPab rabbit polyclonal antibody. Western Blot analysis of GAPDH expression in mouse lung.Western Blot (Tissue lysate)
GAPDH MaxPab rabbit polyclonal antibody. Western Blot analysis of GAPDH expression in human kidney.Western Blot (Cell lysate)
GAPDH MaxPab rabbit polyclonal antibody. Western Blot analysis of GAPDH expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of GAPDH expression in transfected 293T cell line (H00002597-T01) by GAPDH MaxPab polyclonal antibody.
Lane 1: GAPDH transfected lysate(36.10 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — GAPDH
Entrez GeneID
2597GeneBank Accession#
NM_002046Protein Accession#
NP_002037.2Gene Name
GAPDH
Gene Alias
G3PD, GAPD, MGC88685
Gene Description
glyceraldehyde-3-phosphate dehydrogenase
Omim ID
138400Gene Ontology
HyperlinkGene Summary
The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Many pseudogenes similar to this locus are present in the human genome. [provided by RefSeq
Other Designations
OTTHUMP00000174431|OTTHUMP00000174432|aging-associated gene 9 protein|glyceraldehyde 3-phosphate dehydrogenase
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Interactomes
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Pathways
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Glycolysis / Gluconeogenesis
- Metabolic pathways
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Diseases
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Publication Reference
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Structure-function analyses of the G729R 2-oxoadipate dehydrogenase genetic variant associated with L-lysine metabolism disorder.
Zhang X, Nemeria NS, Leandro J, Houten S, Lazarus MB, Gerfen GJ, Ozohanics O, Ambrus A, Nagy B, Brukh R, Jordan F.
The Journal of Biological Chemistry 2020 Jun; 295(23):8078.
Application:WB-Ce, Human, Fibroblasts.
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miR-214 suppresses the osteogenic differentiation of bone marrow-derived mesenchymal stem cells and these effects are mediated through the inhibition of the JNK and p38 pathways.
Guo Y, Li L, Gao J, Chen X, Sang Q.
International Journal of Molecular Medicine 2016 Dec; 39(1):71.
Application:WB-Tr, Rat, Rat bone marrow-derived mesenchymal stem cells.
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Genetic basis of alpha-aminoadipic and alpha-ketoadipic aciduria.
Hagen J, Te Brinke H, Wanders RJ, Knegt AC, Oussoren E, Hoogeboom AJ, Ruijter GJ, Becker D, Schwab KO, Franke I, Duran M, Waterham HR, Sass JO, Houten SM.
Journal of Inherited Metabolic Disease 2015 Sep; 38(5):873.
Application:Immunoblotting, Human, Fibroblasts.
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Structure-function analyses of the G729R 2-oxoadipate dehydrogenase genetic variant associated with L-lysine metabolism disorder.
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