GALNS purified MaxPab rabbit polyclonal antibody (D01P)
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human GALNS protein.
Immunogen
GALNS (NP_000503.1, 1 a.a. ~ 522 a.a) full-length human protein.
Sequence
MAAVVAATRWWQLLLVLSAAGMGASGAPQPPNILLLLMDDMGWGDLGVYGEPSRETPNLDRMAAEGLLFPNFYSANPLCSPSRAALLTGRLPIRNGFYTTNAHARNAYTPQEIVGGIPDSEQLLPELLKKAGYVSKIVGKWHLGHRPQFHPLKHGFDEWFGSPNCHFGPYDNKARPNIPVYRDWEMVGRYYEEFPINLKTGEANLTQIYLQEALDFIKRQARHHPFFLYWAVDATHAPVYASKPFLGTSQRGRYGDAVREIDDSIGKILELLQDLHVADNTFVFFTSDNGAALISAPEQGGSNGPFLCGKQTTFEGGMREPALAWWPGHVTAGQVSHQLGSIMDLFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRLMDRPIFYYRGDTLMAATLGQHKAHFWTWTNSWENFRQGIDFCPGQNVSGVTTHNLEDHTKLPLIFHLGRDPGERFPLSFASAEYQEALSRITSVVQQHQEALVPAQPQLNVCNWAVMNWAPPGCEKLGKCLTPPESIPKKCLWSH
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (86); Rat (85)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
GALNS MaxPab rabbit polyclonal antibody. Western Blot analysis of GALNS expression in human pancreas.Western Blot (Transfected lysate)
Western Blot analysis of GALNS expression in transfected 293T cell line (H00002588-T01) by GALNS MaxPab polyclonal antibody.
Lane 1: GALNS transfected lysate(58.00 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — GALNS
Entrez GeneID
2588GeneBank Accession#
NM_000512.3Protein Accession#
NP_000503.1Gene Name
GALNS
Gene Alias
FLJ17434, FLJ42844, FLJ98217, GALNAC6S, GAS, MPS4A
Gene Description
galactosamine (N-acetyl)-6-sulfate sulfatase
Omim ID
253000Gene Ontology
HyperlinkGene Summary
This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq
Other Designations
chondroitinase
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Interactome
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Pathway
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Disease
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