FUCA1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human FUCA1 partial ORF ( NP_000138, 362 a.a. - 461 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
EAIYASKPWRVQWEKNITSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — FUCA1
Entrez GeneID
2517GeneBank Accession#
NM_000147Protein Accession#
NP_000138Gene Name
FUCA1
Gene Alias
FUCA
Gene Description
fucosidase, alpha-L- 1, tissue
Omim ID
230000Gene Ontology
HyperlinkGene Summary
Alpha-L-fucosidase (EC 3.2.1.51) is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids (Occhiodoro et al., 1989 [PubMed 2803312]). At least 2 separate polymorphic alpha-L-fucosidases are recognized in man: that in tissues, FUCA1, which is deficient in fucosidosis (MIM 230000), and that in plasma, FUCA2 (MIM 136820).[supplied by OMIM
Other Designations
Nbla10230/alpha-L-fucosidase|OTTHUMP00000003009|alpha-L-fucosidase|fucosidase, alpha-L-1, tissue
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Interactome
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Disease
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