FXN 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-FXN full-length
Host
Human
Theoretical MW (kDa)
23.1
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-FXN antibody (H00002395-B01) by Western Blots.
SDS-PAGE Gel
FXN transfected lysate
Western Blot
Lane 1: FXN transfected lysate ( 23.1 KDa).
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — FXN
Entrez GeneID
2395GeneBank Accession#
NM_000144Protein Accession#
NP_000135Gene Name
FXN
Gene Alias
CyaY, FA, FARR, FRDA, MGC57199, X25
Gene Description
frataxin
Gene Ontology
HyperlinkGene Summary
This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
OTTHUMP00000021428
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Interactome
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Disease
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