Products

Western Blot (Transfected lysate)

Western Blot analysis of FGF5 expression in transfected 293T cell line (H00002250-T02) by FGF5 MaxPab polyclonal antibody.

Lane 1: FGF5 transfected lysate(13.00 KDa).
Lane 2: Non-transfected lysate.

In situ Proximity Ligation Assay (Cell)

Proximity Ligation Analysis of protein-protein interactions between FGF5 and MAPK1. HeLa cells were stained with anti-FGF5 rabbit purified polyclonal 1:1200 and anti-MAPK1 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).

Entrez GeneID

2250

GeneBank Accession#

NM_033143

Protein Accession#

NP_149134.1

Gene Name

FGF5

Gene Alias

HBGF-5, Smag-82

Gene Description

fibroblast growth factor 5

Omim ID

165190

Gene Ontology

Hyperlink

Gene Summary

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq

Other Designations

heparin-binding growth factor 5