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FGA Pre-design Chimera RNAi

  • Catalog # : H00002243-R02
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens fibrinogen alpha chain (FGA), transcript variant alpha-E, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_000508
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 2243
  • Gene Name:
  • FGA
  • Gene Alias:
  • Fib2,MGC119422,MGC119423,MGC119425
  • Gene Description:
  • fibrinogen alpha chain
  • Gene Summary:
  • The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq
  • Other Designations:
  • fibrinogen, A alpha polypeptide,fibrinogen, alpha chain, isoform alpha preproprotein,fibrinogen, alpha polypeptide
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