ETS2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ETS2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ETS2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ETS2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ETS2
Entrez GeneID
2114GeneBank Accession#
ETS2Gene Name
ETS2
Gene Alias
ETS2IT1
Gene Description
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
Omim ID
164740Gene Ontology
HyperlinkGene Summary
ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM
Other Designations
OTTHUMP00000115973|oncogene ETS-2|v-ets avian erythroblastosis virus E2 oncogene homolog 2|v-ets avian erythroblastosis virus E26 oncogene homolog 2|v-ets erythroblastosis virus E26 oncogene homolog 2
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Interactome
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Pathway
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Disease
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