Transient overexpression cell lysate was tested with Anti-DVL2 antibody (H00001856-B01) by Western Blots. SDS-PAGE Gel DVL2 transfected lysate. Western Blot Lane 1: DVL2 transfected lysate ( 81.7 KDa) Lane 2: Non-transfected lysate.
Storage Buffer:
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction:
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq
Other Designations:
DSH homolog 2,dishevelled 2,dishevelled 2 (homologous to Drosophila dsh),segment polarity protein dishevelled homolog DVL-2