DVL1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-DVL1 full-length
Host
Human
Theoretical MW (kDa)
47.7
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-DVL1 antibody (H00001855-B01) by Western Blots.
SDS-PAGE Gel
DVL1 transfected lysate.
Western Blot
Lane 1: DVL1 transfected lysate ( 47.7 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — DVL1
Entrez GeneID
1855GeneBank Accession#
NM_182779Protein Accession#
NP_877580Gene Name
DVL1
Gene Alias
DVL, MGC54245
Gene Description
dishevelled, dsh homolog 1 (Drosophila)
Omim ID
601365Gene Ontology
HyperlinkGene Summary
DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. [provided by RefSeq
Other Designations
OTTHUMP00000003104|dishevelled 1|dishevelled 1 (homologous to Drosophila dsh)
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