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DUSP5 Pre-design Chimera RNAi

  • Catalog # : H00001847-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens dual specificity phosphatase 5 (DUSP5), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_004419
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 1847
  • Gene Name:
  • DUSP5
  • Gene Alias:
  • DUSP,HVH3
  • Gene Description:
  • dual specificity phosphatase 5
  • Gene Summary:
  • The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000020476,VH1-like phosphatase 3,serine/threonine specific protein phosphatase
  • Gene Pathway
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