DNASE2 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of DNASE2 transfected lysate using rabbit polyclonal anti-DNASE2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-DNASE2.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (72%); Rat (73%)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of DNASE2 transfected lysate using rabbit polyclonal anti-DNASE2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-DNASE2.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-DNASE2 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-DNASE2 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — DNASE2
Entrez GeneID
1777Gene Name
DNASE2
Gene Alias
DNASE2A, DNL, DNL2
Gene Description
deoxyribonuclease II, lysosomal
Omim ID
126350Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record. [provided by RefSeq
Other Designations
DNase II alpha|DNase II, lysosomal|R31240_2|acid DNase
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Interactome
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Pathway
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Disease
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