CYB5R3 polyclonal antibody (A01)
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Specifications
Product Description
Mouse polyclonal antibody raised against a full-length recombinant CYB5R3.
Immunogen
CYB5R3 (AAH04821, 1 a.a. ~ 301 a.a) full-length recombinant protein with GST tag.
Sequence
MGAQLSTLGHMVLFPVWFLYSLLMKLFQRSTPAITLESPDIKYPLRLIDREIISHDTRRFRFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISSDDDKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKSNPIIRTVKSVGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNKHSARFKLWYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLDHVGHPTERCFVF
Host
Mouse
Reactivity
Human, Mouse, Rat
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (59.22 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
CYB5R3 polyclonal antibody (A01), Lot # AUL1060606QCS1. Western Blot analysis of CYB5R3 expression in PC-12.Western Blot (Cell lysate)
CYB5R3 polyclonal antibody (A01), Lot # AUL1060606QCS1. Western Blot analysis of CYB5R3 expression in NIH/3T3.Western Blot (Cell lysate)
CYB5R3 polyclonal antibody (A01), Lot # AUL1060606QCS1 Western Blot analysis of CYB5R3 expression in A-431 ( Cat # L015V1 ).Western Blot (Cell lysate)
CYB5R3 polyclonal antibody (A01), Lot # AUL1060606QCS1. Western Blot analysis of CYB5R3 expression in Raw 264.7.Western Blot (Recombinant protein)
ELISA
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Gene Info — CYB5R3
Entrez GeneID
1727GeneBank Accession#
BC004821Protein Accession#
AAH04821Gene Name
CYB5R3
Gene Alias
B5R, DIA1
Gene Description
cytochrome b5 reductase 3
Omim ID
250800Gene Ontology
HyperlinkGene Summary
This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. These two forms are resulted from alternative splicing of the gene. Mutations in this gene cause methemoglobinemias. [provided by RefSeq
Other Designations
NADH-cytochrome b5 reductase|OTTHUMP00000028761|cytochrome b5 reductase|diaphorase (NADH) (cytochrome b-5 reductase)
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Interactomes
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Pathways
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Diseases
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