DHCR24 purified MaxPab mouse polyclonal antibody (B01P)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of DHCR24 expression in transfected 293T cell line (H00001718-T01) by DHCR24 MaxPab polyclonal antibody.
Lane 1: DHCR24 transfected lysate(56.76 KDa).
Lane 2: Non-transfected lysate.
-
Specification
Product Description
Mouse polyclonal antibody raised against a full-length human DHCR24 protein.
Immunogen
DHCR24 (NP_055577.1, 1 a.a. ~ 516 a.a) full-length human protein.
Sequence
MEPAVSLAVCALLFLLWVRLKGLEFVLIHQRWVFVCLFLLPLSLIFDIYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKEQGSKTFMCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALLTSIGWTLPVLPELDDLTVGGLIMGTGIESSSHKYGLFQHICTAYELVLADGSFVRCTPSENSDLFYAVPWSCGTLGFLVAAEIRIIPAKKYVKLRFEPVRGLEAICAKFTHESQRQENHFVEGLLYSLDEAVIMTGVMTDEAEPSKLNSIGNYYKPWFFKHVENYLKTNREGLEYIPLRHYYHRHTRSIFWELQDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCLQQALHTFQNDIHVYPIWLCPFILPSQPGLVHPKGNEAELYIDIGAYGEPRVKHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLREKLGCQDAFPEVYDKICKAARH
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (97)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot (Transfected lysate)
Western Blot analysis of DHCR24 expression in transfected 293T cell line (H00001718-T01) by DHCR24 MaxPab polyclonal antibody.
Lane 1: DHCR24 transfected lysate(56.76 KDa).
Lane 2: Non-transfected lysate.
-
Gene Info — DHCR24
Entrez GeneID
1718GeneBank Accession#
NM_014762.2Protein Accession#
NP_055577.1Gene Name
DHCR24
Gene Alias
KIAA0018, Nbla03646, SELADIN1, seladin-1
Gene Description
24-dehydrocholesterol reductase
Gene Ontology
HyperlinkGene Summary
This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq
Other Designations
3 beta-hydroxysterol delta 24-reductase|OTTHUMP00000011685|diminuto/dwarf1 homolog|putative protein product of Nbla03646|selective AD indicator 1
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Bacterial colonization of host cells in the absence of cholesterol.
Gilk SD, Cockrell DC, Luterbach C, Hansen B, Knodler LA, Ibarra JA, Steele-Mortimer O, Heinzen RA.
PLOS Pathogens 2013 Jan; 9(1):e1003107.
Application：WB, Mouse, MEF cells.
-
Bacterial colonization of host cells in the absence of cholesterol.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com