GADD45A (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human GADD45A full-length ORF ( AAH11757.1, 1 a.a. - 165 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLAADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPPDLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
44.7
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GADD45A
Entrez GeneID
1647GeneBank Accession#
BC011757.2Protein Accession#
AAH11757.1Gene Name
GADD45A
Gene Alias
DDIT1, GADD45
Gene Description
growth arrest and DNA-damage-inducible, alpha
Omim ID
126335Gene Ontology
HyperlinkGene Summary
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. [provided by RefSeq
Other Designations
DNA damage-inducible transcript 1|DNA damage-inducible transcript-1|DNA-damage-inducible transcript 1|OTTHUMP00000010979|growth arrest and DNA-damage-inducible 45 alpha
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Interactome
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Pathway
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Disease
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