GADD45A rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human GADD45A peptide using ARM Technology.
Immunogen
A synthetic peptide of human GADD45A is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human GADD45A peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — GADD45A
Entrez GeneID
1647GeneBank Accession#
GADD45AGene Name
GADD45A
Gene Alias
DDIT1, GADD45
Gene Description
growth arrest and DNA-damage-inducible, alpha
Omim ID
126335Gene Ontology
HyperlinkGene Summary
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. [provided by RefSeq
Other Designations
DNA damage-inducible transcript 1|DNA damage-inducible transcript-1|DNA-damage-inducible transcript 1|OTTHUMP00000010979|growth arrest and DNA-damage-inducible 45 alpha
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Interactome
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Disease
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