DCK 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
DCK transfected lysate.
Western Blot
Lane 1: DCK transfected lysate ( 28.6 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-DCK full-length
Host
Human
Theoretical MW (kDa)
28.6
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-DCK antibody (H00001633-B01P) by Western Blots.
SDS-PAGE Gel
DCK transfected lysate.
Western Blot
Lane 1: DCK transfected lysate ( 28.6 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — DCK
Entrez GeneID
1633GeneBank Accession#
NM_000788Protein Accession#
NP_000779Gene Name
DCK
Gene Alias
MGC117410, MGC138632
Gene Description
deoxycytidine kinase
Omim ID
125450Gene Ontology
HyperlinkGene Summary
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
- Acute Disease
- Adenocarcinoma
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Kidney Failure
- Leukemia
- Neoplasms
- Neutropenia
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