CTSH purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human CTSH protein.
Immunogen
CTSH (AAH02479, 1 a.a. ~ 335 a.a) full-length human protein.
Sequence
MWATLPLLCAGAWLLGVPVCGAAELSVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
CTSH MaxPab polyclonal antibody. Western Blot analysis of CTSH expression in human placenta.Western Blot (Transfected lysate)
Western Blot analysis of CTSH expression in transfected 293T cell line (H00001512-T01) by CTSH MaxPab polyclonal antibody.
Lane 1: CTSH transfected lysate(36.96 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to CTSH on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml] -
Gene Info — CTSH
Entrez GeneID
1512GeneBank Accession#
BC002479Protein Accession#
AAH02479Gene Name
CTSH
Gene Alias
ACC-4, ACC-5, CPSB, DKFZp686B24257, MGC1519, minichain
Gene Description
cathepsin H
Omim ID
116820Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
N-benzoylarginine-beta-naphthylamide hydrolase|aleurain|cathepsin B3|cathepsin BA
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Interactome
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Pathway
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Disease
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Publication Reference
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The Expression and Activity of Cathepsins D, H and K in Asthmatic Airways.
Faiz A, Tjin G, Harkness L, Weckmann M, Bao S, Black JL, Oliver BG, Burgess JK.
PLoS One 2013 Mar; 8(3):e57245.
Application:IHC, Human, Human airway tissues.
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The Expression and Activity of Cathepsins D, H and K in Asthmatic Airways.
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