CTSB 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
CTSB transfected lysate.
Western Blot
Lane 1: CTSB transfected lysate ( 37.4 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CTSB full-length
Host
Human
Theoretical MW (kDa)
37.4
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CTSB antibody (H00001508-B01) by Western Blots.
SDS-PAGE Gel
CTSB transfected lysate.
Western Blot
Lane 1: CTSB transfected lysate ( 37.4 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CTSB
Entrez GeneID
1508GeneBank Accession#
NM_001908.3Protein Accession#
NP_001899.1Gene Name
CTSB
Gene Alias
APPS, CPSB
Gene Description
cathepsin B
Omim ID
116810Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
APP secretase|OTTHUMP00000116009|amyloid precursor protein secretase|cathepsin B1|cysteine protease|preprocathepsin B
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Interactome
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Disease
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