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- Home > Products > siRNA/Chimera > Pre-design Chimera > Others > CTH Pre-design Chimera RNAi
CTH Pre-design Chimera RNAi
- Catalog # : H00001491-R02
- Visit Frequency :
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- Price
- In Stock
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- 10 nmol
- USD $ 239
- order now, ship in 2 weeks
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- 20 nmol
- USD $ 289
- order now, ship in 2 weeks
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Email : sales@abnova.com
Phone : +1-909-992-0619 (new)
Fax : +1-909-992-3401- Products will be shipped directly to the customer.
- Specification
- Product Description:
- Homo sapiens cystathionase (cystathionine gamma-lyase) (CTH), transcript variant 2, mRNA.
- Reactivity:
- Human
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_153742
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 1491
- Gene Name:
- CTH
- Gene Alias:
- MGC9471
- Gene Description:
- cystathionase (cystathionine gamma-lyase)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
- Other Designations:
- OTTHUMP00000010945,OTTHUMP00000010946,cystathionase,cysteine desulfhydrase,gamma-cystathionase,homoserine deaminase,homoserine dehydratase
- Related Disease
- Atherosclerosis
- Atherosclerosis
- Calcinosis
- Cardiovascular Diseases
- Carotid Stenosis
- Cleft Lip
- Cleft Palate
- Coronary Artery Disease
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Hypertension
- Infertility, Female
- Lung Neoplasms
- Pulmonary Disease, Chronic Obstructive
- Spinal Dysraphism
- Urinary Bladder Neoplasms
- Werner syndrome
