CREM 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
Western Blot
Lane 1: CREM transfected lysate ( 14.9 KDa)
Lane 2: Non-transfected lysate.
SDS-PAGE Gel
CREM transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CREM full-length
Host
Human
Theoretical MW (kDa)
15.18
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CREM antibody (H00001390-B01) by Western Blots.
Western Blot
Lane 1: CREM transfected lysate ( 14.9 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
CREM transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CREM
Entrez GeneID
1390GeneBank Accession#
NM_001881.2Protein Accession#
-Gene Name
CREM
Gene Alias
ICER, MGC111110, MGC17881, MGC41893, hCREM-2
Gene Description
cAMP responsive element modulator
Omim ID
123812Gene Ontology
HyperlinkGene Summary
This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq
Other Designations
OTTHUMP00000019442|OTTHUMP00000019443|OTTHUMP00000019444|OTTHUMP00000019446|OTTHUMP00000019448|cAMP response element modulator|hCREM 2alpha-b protein|hCREM 2beta-a protein|inducible cAMP early repressor ICER
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Interactome
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Disease
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