CLPS monoclonal antibody (M01), clone 8A8
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More Files
- More Functions
Immunoprecipitation
Immunoprecipitation of CLPS transfected lysate using anti-CLPS monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with CLPS MaxPab rabbit polyclonal antibody.
Western Blot detection against Immunogen (35.64 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CLPS.
Immunogen
CLPS (NP_001823, 23 a.a. ~ 112 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GIIINLENGELCMNSAQCKSNCCQHSSALGLARCTSMASENSECSVKTLYGIYYKCPCERGLTCEGDKTIVGSITNTNFGICHDAGRSKQ
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.64 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunoprecipitation
Immunoprecipitation of CLPS transfected lysate using anti-CLPS monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with CLPS MaxPab rabbit polyclonal antibody.ELISA
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Gene Info — CLPS
Entrez GeneID
1208GeneBank Accession#
NM_001832Protein Accession#
NP_001823Gene Name
CLPS
Gene Alias
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Gene Description
colipase, pancreatic
Omim ID
120105Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. [provided by RefSeq
Other Designations
OTTHUMP00000016271|colipase|pancreatic colipase preproprotein
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Interactome
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Disease
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