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TPP1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00001200-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-TPP1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 62.04
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-TPP1 antibody (H00001200-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00001200-T01
    TPP1 transfected lysate.
    Western Blot
    QC Testing of H00001200-T01
    Lane 1: TPP1 transfected lysate ( 62.04 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 1200
  • Gene Name:
  • TPP1
  • Gene Alias:
  • CLN2,GIG1,LPIC,MGC21297
  • Gene Description:
  • tripeptidyl peptidase I
  • Gene Summary:
  • This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq
  • Other Designations:
  • ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease),growth-inhibiting protein 1,lysosomal pepstatin insensitive protease,tripeptidyl aminopeptidase,tripeptidyl-peptidase I
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