ERCC8 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Cell lysate)
ERCC8 MaxPab polyclonal antibody. Western Blot analysis of ERCC8 expression in NIH/3T3.
Western Blot (Transfected lysate)
Western Blot analysis of ERCC8 expression in transfected 293T cell line (H00001161-T01) by ERCC8 MaxPab polyclonal antibody.
Lane 1: ERCC8 transfected lysate(43.56 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to ERCC8 on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human ERCC8 protein.
Immunogen
ERCC8 (NP_000073.1, 1 a.a. ~ 396 a.a) full-length human protein.
Sequence
MLGFLSARQTGLEDPLRLRRAESTRRVLGLELNKDRDVERIHGGGINTLDIEPVEGRYMLSGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKFTVSCGCSSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILAWVPSLYEPVPDDDETTTKSQLNPAFEDAWSSSDEEG
Host
Mouse
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ERCC8 MaxPab polyclonal antibody. Western Blot analysis of ERCC8 expression in NIH/3T3.Western Blot (Transfected lysate)
Western Blot analysis of ERCC8 expression in transfected 293T cell line (H00001161-T01) by ERCC8 MaxPab polyclonal antibody.
Lane 1: ERCC8 transfected lysate(43.56 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to ERCC8 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — ERCC8
Entrez GeneID
1161GeneBank Accession#
NM_000082.1Protein Accession#
NP_000073.1Gene Name
ERCC8
Gene Alias
CKN1, CSA
Gene Description
excision repair cross-complementing rodent repair deficiency, complementation group 8
Gene Ontology
HyperlinkGene Summary
This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. [provided by RefSeq
Other Designations
Cockayne syndrome WD-repeat protein CSA|DNA excision repair protein ERCC-8
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Interactome
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Pathway
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Disease
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