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Last updated: 2014/8/18

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CIDEA Pre-design Chimera RNAi

  • Catalog # : H00001149-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens cell death-inducing DFFA-like effector a (CIDEA), transcript variant 1, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_001279
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 1149
  • Gene Name:
  • CIDEA
  • Gene Alias:
  • CIDE-A
  • Gene Description:
  • cell death-inducing DFFA-like effector a
  • Gene Summary:
  • This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq
  • Other Designations:
  • cell death activator
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