CIDEA (Human) IP-WB Antibody Pair
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More Files
- More Functions
Immunoprecipitation of CIDEA transfected lysate using rabbit polyclonal anti-CIDEA and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-CIDEA.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of CIDEA transfected lysate using rabbit polyclonal anti-CIDEA and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-CIDEA.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-CIDEA (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-CIDEA (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — CIDEA
Entrez GeneID
1149Gene Name
CIDEA
Gene Alias
CIDE-A
Gene Description
cell death-inducing DFFA-like effector a
Omim ID
604440Gene Ontology
HyperlinkGene Summary
This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq
Other Designations
cell death activator
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Interactome
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Disease
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