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AKR1C4 MaxPab mouse polyclonal antibody (B01)MaxPab

  • Catalog # : H00001109-B01
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human AKR1C4 protein.
  • Immunogen:
  • AKR1C4 (AAH20744.1, 1 a.a. ~ 323 a.a) full-length human protein.
  • Sequence:
  • MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYPFSDEY
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • AKR1C4 MaxPab polyclonal antibody. Western Blot analysis of AKR1C4 expression in human liver.
  • Protocol Download
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of AKR1C4 expression in transfected 293T cell line (H00001109-T01) by AKR1C4 MaxPab polyclonal antibody.

    Lane 1: AKR1C4 transfected lysate(35.53 KDa).
    Lane 2: Non-transfected lysate.
  • Protocol Download
  • Detection Antibody
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Detection Antibody
  • Gene Information
  • Entrez GeneID:
  • 1109
  • Gene Name:
  • AKR1C4
  • Gene Alias:
  • 3-alpha-HSD,C11,CDR,CHDR,DD4,HAKRA,MGC22581
  • Gene Description:
  • aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
  • Gene Summary:
  • This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq
  • Other Designations:
  • 3 alpha-hydroxysteroid dehydrogenase/dihydrodiol dehydrogenase 4,OTTHUMP00000018997,aldo-keto reductase family 1, member C4,chlordecone reductase,dihydrodiol dehydrogenase 4,dihydrodiol dehydrogenase isozyme DD4,type I 3-alpha-hydroxysteroid dehydrogenase
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