CDH11 monoclonal antibody (M01), clone 4D10
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CDH11.
Immunogen
CDH11 (NP_001788, 509 a.a. ~ 617 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PIVTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLST
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (98)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.73 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CDH11 is approximately 0.3ng/ml as a capture antibody.ELISA
-
Gene Info — CDH11
Entrez GeneID
1009GeneBank Accession#
NM_001797Protein Accession#
NP_001788Gene Name
CDH11
Gene Alias
CAD11, CDHOB, OB, OSF-4
Gene Description
cadherin 11, type 2, OB-cadherin (osteoblast)
Omim ID
600023Gene Ontology
HyperlinkGene Summary
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq
Other Designations
OB-cadherin|cadherin 11, type 2|cadherin-11|osteoblast cadherin
-
Interactome
-
Disease
-
Publication Reference
-
Development of a Surface Plasmon Resonance Biosensor for Real-Time Detection of Osteogenic Differentiation in Live Mesenchymal Stem Cells.
Kuo YC, Ho JH, Yen TJ, Chen HF, Lee OK.
PLoS One 2011 Jul; 6(7):e22382.
Application:Func, Human, Hep-3B, Mesenchymal stem cells, SaOS2 cells.
-
Development of a Surface Plasmon Resonance Biosensor for Real-Time Detection of Osteogenic Differentiation in Live Mesenchymal Stem Cells.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com