CD53 MaxPab mouse polyclonal antibody (B01)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of CD53 expression in transfected 293T cell line (H00000963-T01) by CD53 MaxPab polyclonal antibody.
Lane 1: CD53 transfected lysate(24.09 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human CD53 protein.
Immunogen
CD53 (NP_000551.1, 1 a.a. ~ 219 a.a) full-length human protein.
Sequence
MGMSSLKLLKYVLFFFNLLFWICGCCILGFGIYLLIHNNFGVLFHNLPSLTLGNVFVIVGSIIMVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHRYHSDNSTKAAWDSIQSFLQCCGINGTSDWTSGPPASCPSDRKVEGCYAKARLWFHSNFLYIGIITICVCVIEVLGMSFALTLNCQIDKTSQTIGL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (81)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CD53 expression in transfected 293T cell line (H00000963-T01) by CD53 MaxPab polyclonal antibody.
Lane 1: CD53 transfected lysate(24.09 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CD53
Entrez GeneID
963GeneBank Accession#
NM_000560.3Protein Accession#
NP_000551.1Gene Name
CD53
Gene Alias
MOX44, TSPAN25
Gene Description
CD53 molecule
Omim ID
151525Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
Other Designations
CD53 antigen|CD53 glycoprotein|CD53 tetraspan antigen|OTTHUMP00000013686|OTTHUMP00000059505|antigen MOX44 identified by monoclonal antibody MRC-OX44|cell surface antigen|leukocyte surface antigen CD53|tetraspanin-25|transmembrane glycoprotein
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Interactome
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Disease
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