SCARB2 monoclonal antibody (M01), clone 1C8
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SCARB2.
Immunogen
SCARB2 (NP_005497, 339 a.a. ~ 437 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
FPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQINIYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMINTTLIITN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (85); Rat (86)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SCARB2 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — SCARB2
Entrez GeneID
950GeneBank Accession#
NM_005506Protein Accession#
NP_005497Gene Name
SCARB2
Gene Alias
AMRF, CD36L2, HLGP85, LIMPII, SR-BII
Gene Description
scavenger receptor class B, member 2
Omim ID
602257Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Studies of the similar protein in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. Deficiency of the similar protein in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. [provided by RefSeq
Other Designations
85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2|CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II)|lysosomal integral membrane protein II
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Interactome
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Disease
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