CBR3 MaxPab mouse polyclonal antibody (B01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human CBR3 protein.
Immunogen
CBR3 (NP_001227.1, 1 a.a. ~ 277 a.a) full-length human protein.
Sequence
MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVEEGAETPVYLALLPPDATEPQGQLVHDKVVQNW
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Tissue lysate)
CBR3 MaxPab polyclonal antibody. Western Blot analysis of CBR3 expression in human colon.Western Blot (Transfected lysate)
Western Blot analysis of CBR3 expression in transfected 293T cell line (H00000874-T01) by CBR3 MaxPab polyclonal antibody.
Lane 1: CBR3 transfected lysate(30.47 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CBR3
Entrez GeneID
874GeneBank Accession#
NM_001236.3Protein Accession#
NP_001227.1Gene Name
CBR3
Gene Alias
SDR21C2, hCBR3
Gene Description
carbonyl reductase 3
Omim ID
603608Gene Ontology
HyperlinkGene Summary
Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq
Other Designations
NADPH-dependent carbonyl reductase 3|carbonyl reductase (NADPH) 3|short chain dehydrogenase/reductase family 21C, member 2
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Interactome
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Pathway
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Disease
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Publication Reference
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Naturally Occurring Variants of Human CBR3 Alter Anthracycline In Vitro Metabolism.
Bains OS, Karkling MJ, Lubieniecka JM, Grigliatti TA, Reid RE, Riggs KW.
The Journal of Pharmacology and Experimental Therapeutics 2010 Mar; 332(3):755.
Application:WB, Escherichia coli, Human, BL21 (DE3) pLysS competent cells, liver.
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Naturally Occurring Variants of Human CBR3 Alter Anthracycline In Vitro Metabolism.
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