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RUNX1T1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00000862-T01
  • Visit Frequency :
  • Countries :
  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-RUNX1T1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 63.58
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-RUNX1T1 antibody (H00000862-B02) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00000862-T01
    RUNX1T1 transfected lysate.
    Western Blot
    QC Testing of H00000862-T01
    Lane 1: RUNX1T1 transfected lysate ( 63.58 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 862
  • Protein Accession#:
  • -
  • Gene Name:
  • RUNX1T1
  • Gene Alias:
  • AML1T1,CBFA2T1,CDR,ETO,MGC2796,MTG8,MTG8b,ZMYND2
  • Gene Description:
  • runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
  • Gene Summary:
  • The protein encoded by this gene is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Several transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • acute myelogenous leukemia 1 translocation 1 protein,acute myelogenous leukemia 1 translocation 1, cyclin-D related,core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related,eight twenty one protein,myeloid translocation gene
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