CAMK2B (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human CAMK2B partial ORF ( NP_742078, 405 a.a. - 502 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
FEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.52
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CAMK2B
Entrez GeneID
816GeneBank Accession#
NM_172081Protein Accession#
NP_742078Gene Name
CAMK2B
Gene Alias
CAM2, CAMK2, CAMKB, MGC29528
Gene Description
calcium/calmodulin-dependent protein kinase II beta
Omim ID
607707Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
CaM kinase II beta subunit|CaM-kinase II beta chain|CaMK-II beta subunit|OTTHUMP00000159355|OTTHUMP00000159356|calcium/calmodulin-dependent protein kinase (CaM kinase) II beta|calcium/calmodulin-dependent protein kinase type II beta chain|proline rich cal
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Interactome
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Disease
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